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Pharmacogenomics, explained by the pharmacists who read the reports
Plain-language writing on CYP2D6 and CYP2C19 metabolizer status, drug gene interactions, antidepressant and statin selection, insurance coverage, and what a pharmacogenomic test can and cannot tell you.
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Featured · Pain managementWhy Do Statins Cause Muscle Pain? Causes & Risk Factors
Sore legs & heavy shoulders. Aching that started right around the time you filled a new cholesterol prescription. If this sounds familiar, you’re dealing with one of the most common complaints tied to statins: muscle pain. Doctors call it statin-induced myopathy once…
6 min read
Latest articles
Every article is written or reviewed by a licensed pharmacist at our Dallas laboratory and dated so you can see how current the guidance is.
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CYP2D6 Inhibitors: Working, Common Drugs, & More
CYP2D6 (Cytochrome P450 2D6) is a crucial liver enzyme responsible for metabolising approximately 25% of all clinically used drugs, including antidepressants, opioids, beta-blockers, and antipsychotics. Variations…
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Lumbrokinase Benefits and Mechanisms I Role of CYP450 Enzymes
Derived from earthworms, particularly Lumbricus rubellus and Lumbricus bimastus, Lumbrokinase is a fibrinolytic enzyme. It can break down fibrinogen (a soluble plasma protein synthesised in the…
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Assessing Oncogenicity’s Role in Drug Development and Safety
Oncogenicity refers to a substance’s ability to activate genes that may cause cancer. This could involve pharmaceutical compounds, chemicals, or genetic changes. It increases the risk…
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Histamine Dump at Night Symptoms I Background & Preventions
A condition often referred to as a “histamine dumping,” occurs when there’s an excessive release of histamine (a naturally occurring compound involved in immune responses, digestion,…
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Understanding The COMT Gene Mutation Supplements
To understand COMT Gene Mutation Supplements, it’s important to first know the COMT gene and its mutation. The COMT (catechol-O-methyltransferase) gene encodes an enzyme (COMT enzyme)…
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Pharmacogenetic Testing Cost in the USA in 2026
The Pharmacogenetic Testing Costs vary based on the test complexity and insurance coverage. Some medications, especially mental health ones, have been indicated by the FDA to…
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What Is Gene Sight Testing? Pros, Cons, and More
Pharmacogenomic testing, also known as PGx testing, gives insights into your genetic makeup. In case of certain medications, this information is utilised to tailor treatments that…
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Dutch Testing: Working, Costs, and Comparison
Hormonal imbalances can significantly impact overall health, affecting everything from energy levels to mood and metabolism. The blood tests in this regard provide insights into hormone…
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OCD vs Anxiety I Symptoms, Medication, and More
Obsessive-Compulsive Disorder (OCD) and anxiety disorders are two of the most common mental health conditions in the United States. Although they share some similarities, they differ…
4 min read
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