Medication list
Genes and drugs covered by the RPh Labs PGx panel
Search the panel by drug, brand name, gene or specialty. Each row shows the gene that drives the interaction, its CPIC guideline level, and whether the FDA label carries pharmacogenomic information.
This list is educational. Nothing here is a recommendation to start, stop or change a medication.
| Generic drug | Brand name | Gene | Specialty category | CPIC level | PGx on FDA label |
|---|---|---|---|---|---|
| Amitriptyline | Elavil | CYP2D6 · CYP2C19 | Psychiatry | A | Yes |
| Nortriptyline | Pamelor | CYP2D6 | Psychiatry | A | Yes |
| Imipramine | Tofranil | CYP2D6 · CYP2C19 | Psychiatry | A | Yes |
| Desipramine | Norpramin | CYP2D6 | Psychiatry | A | Yes |
| Doxepin | Silenor | CYP2D6 · CYP2C19 | Psychiatry | A | Yes |
| Clomipramine | Anafranil | CYP2D6 · CYP2C19 | Psychiatry | A | Yes |
| Trimipramine | Surmontil | CYP2D6 · CYP2C19 | Psychiatry | A | Yes |
| Protriptyline | Vivactil | CYP2D6 | Psychiatry | A | Yes |
| Amoxapine | Asendin | CYP2D6 | Psychiatry | C | No |
| Maprotiline | Ludiomil | CYP2D6 | Psychiatry | C | No |
| Citalopram | Celexa | CYP2C19 | Psychiatry | A | Yes |
| Escitalopram | Lexapro | CYP2C19 | Psychiatry | A | Yes |
| Sertraline | Zoloft | CYP2C19 | Psychiatry | A | Yes |
| Paroxetine | Paxil | CYP2D6 | Psychiatry | A | Yes |
| Fluoxetine | Prozac | CYP2D6 | Psychiatry | A | Yes |
| Fluvoxamine | Luvox | CYP2D6 | Psychiatry | A | Yes |
| Venlafaxine | Effexor | CYP2D6 | Psychiatry | A | Yes |
| Desvenlafaxine | Pristiq | CYP2D6 | Psychiatry | C | No |
| Duloxetine | Cymbalta | CYP1A2 · CYP2D6 | Psychiatry | C | No |
| Vortioxetine | Trintellix | CYP2D6 | Psychiatry | A | Yes |
| Mirtazapine | Remeron | CYP2D6 | Psychiatry | C | No |
| Bupropion | Wellbutrin | CYP2B6 | Psychiatry | C | Yes |
| Trazodone | Desyrel | CYP2D6 | Psychiatry | C | No |
| Vilazodone | Viibryd | CYP2C19 | Psychiatry | C | No |
| Nefazodone | Serzone | CYP3A4 | Psychiatry | C | No |
| Atomoxetine | Strattera | CYP2D6 | Psychiatry | A | Yes |
| Amphetamine | Adderall | CYP2D6 | Psychiatry | C | Yes |
| Lisdexamfetamine | Vyvanse | CYP2D6 | Psychiatry | C | Yes |
| Methylphenidate | Ritalin | CES1 | Psychiatry | C | No |
| Modafinil | Provigil | CYP2C19 | Psychiatry | C | No |
| Aripiprazole | Abilify | CYP2D6 | Psychiatry | B | Yes |
| Brexpiprazole | Rexulti | CYP2D6 | Psychiatry | B | Yes |
| Cariprazine | Vraylar | CYP3A4 | Psychiatry | C | No |
| Risperidone | Risperdal | CYP2D6 | Psychiatry | B | Yes |
| Paliperidone | Invega | CYP2D6 | Psychiatry | C | Yes |
| Iloperidone | Fanapt | CYP2D6 | Psychiatry | B | Yes |
| Ziprasidone | Geodon | CYP2D6 | Psychiatry | C | No |
| Quetiapine | Seroquel | CYP3A4 | Psychiatry | C | No |
| Olanzapine | Zyprexa | CYP1A2 | Psychiatry | C | No |
| Clozapine | Clozaril | CYP1A2 · CYP2D6 | Psychiatry | C | Yes |
| Lurasidone | Latuda | CYP3A4 | Psychiatry | C | No |
| Asenapine | Saphris | CYP1A2 | Psychiatry | C | No |
| Haloperidol | Haldol | CYP2D6 | Psychiatry | B | Yes |
| Pimozide | Orap | CYP2D6 | Psychiatry | A | Yes |
| Thioridazine | Mellaril | CYP2D6 | Psychiatry | B | Yes |
| Perphenazine | Trilafon | CYP2D6 | Psychiatry | C | Yes |
| Fluphenazine | Prolixin | CYP2D6 | Psychiatry | C | No |
| Chlorpromazine | Thorazine | CYP2D6 | Psychiatry | C | No |
| Buspirone | Buspar | CYP3A4 | Psychiatry | C | No |
| Diazepam | Valium | CYP2C19 | Psychiatry | C | No |
| Clobazam | Onfi | CYP2C19 | Neurology | A | Yes |
| Alprazolam | Xanax | CYP3A4 | Psychiatry | C | No |
| Clonazepam | Klonopin | CYP3A4 | Psychiatry | C | No |
| Zolpidem | Ambien | CYP2C19 | Psychiatry | C | No |
| Eszopiclone | Lunesta | CYP3A4 | Psychiatry | C | No |
| Flurazepam | Dalmane | CYP3A4 | Psychiatry | C | No |
| Pitolisant | Wakix | CYP2D6 | Neurology | B | Yes |
| Carbamazepine | Tegretol | HLA-B*15:02 · HLA-A*31:01 | Neurology | A | Yes |
| Oxcarbazepine | Trileptal | HLA-B*15:02 | Neurology | A | Yes |
| Eslicarbazepine | Aptiom | HLA-B*15:02 | Neurology | C | No |
| Phenytoin | Dilantin | CYP2C9 · HLA-B*15:02 | Neurology | A | Yes |
| Fosphenytoin | Cerebyx | CYP2C9 · HLA-B*15:02 | Neurology | A | Yes |
| Lamotrigine | Lamictal | HLA-B*15:02 | Neurology | C | No |
| Valproic acid | Depakote | POLG | Neurology | B | Yes |
| Phenobarbital | Luminal | CYP2C19 | Neurology | C | No |
| Lacosamide | Vimpat | CYP2C19 | Neurology | C | No |
| Brivaracetam | Briviact | CYP2C19 | Neurology | C | No |
| Zonisamide | Zonegran | CYP3A4 | Neurology | C | No |
| Siponimod | Mayzent | CYP2C9 | Neurology | A | Yes |
| Ozanimod | Zeposia | CYP2C8 | Neurology | C | No |
| Tetrabenazine | Xenazine | CYP2D6 | Neurology | B | Yes |
| Deutetrabenazine | Austedo | CYP2D6 | Neurology | B | Yes |
| Valbenazine | Ingrezza | CYP2D6 | Neurology | B | Yes |
| Donepezil | Aricept | CYP2D6 | Neurology | C | No |
| Galantamine | Razadyne | CYP2D6 | Neurology | C | No |
| Dextromethorphan–quinidine | Nuedexta | CYP2D6 | Neurology | B | Yes |
| Amifampridine | Firdapse | NAT2 | Neurology | B | Yes |
| Tizanidine | Zanaflex | CYP1A2 | Neurology | C | No |
| Cyclobenzaprine | Flexeril | CYP2D6 | Neurology | C | No |
| Carisoprodol | Soma | CYP2C19 | Pain management | C | Yes |
| Clopidogrel | Plavix | CYP2C19 | Cardiology | A | Yes |
| Prasugrel | Effient | CYP2C19 | Cardiology | A | Yes |
| Ticagrelor | Brilinta | CYP2C19 | Cardiology | A | No |
| Warfarin | Coumadin | CYP2C9 · VKORC1 · CYP4F2 | Cardiology | A | Yes |
| Acenocoumarol | Sintrom | CYP2C9 · VKORC1 | Cardiology | A | No |
| Phenprocoumon | Marcoumar | CYP2C9 · VKORC1 | Cardiology | A | No |
| Dabigatran | Pradaxa | CES1 | Cardiology | C | No |
| Rivaroxaban | Xarelto | ABCB1 | Cardiology | C | No |
| Apixaban | Eliquis | ABCB1 | Cardiology | C | No |
| Cilostazol | Pletal | CYP2C19 | Cardiology | C | No |
| Simvastatin | Zocor | SLCO1B1 | Cardiology | A | No |
| Atorvastatin | Lipitor | SLCO1B1 | Cardiology | A | No |
| Rosuvastatin | Crestor | SLCO1B1 · ABCG2 | Cardiology | A | No |
| Pravastatin | Pravachol | SLCO1B1 | Cardiology | A | No |
| Fluvastatin | Lescol | CYP2C9 | Cardiology | A | Yes |
| Lovastatin | Mevacor | SLCO1B1 | Cardiology | A | No |
| Pitavastatin | Livalo | SLCO1B1 | Cardiology | A | No |
| Metoprolol | Lopressor | CYP2D6 | Cardiology | B | Yes |
| Carvedilol | Coreg | CYP2D6 | Cardiology | C | No |
| Nebivolol | Bystolic | CYP2D6 | Cardiology | C | Yes |
| Propranolol | Inderal | CYP2D6 | Cardiology | C | No |
| Timolol | Blocadren | CYP2D6 | Cardiology | C | No |
| Propafenone | Rythmol | CYP2D6 | Cardiology | B | Yes |
| Flecainide | Tambocor | CYP2D6 | Cardiology | B | Yes |
| Mexiletine | Mexitil | CYP2D6 | Cardiology | C | No |
| Amiodarone | Cordarone | CYP2C9 | Cardiology | C | No |
| Digoxin | Lanoxin | ABCB1 | Cardiology | C | No |
| Losartan | Cozaar | CYP2C9 | Cardiology | C | No |
| Irbesartan | Avapro | CYP2C9 | Cardiology | C | No |
| Torsemide | Demadex | CYP2C9 | Cardiology | C | No |
| Bosentan | Tracleer | CYP2C9 | Cardiology | C | No |
| Hydralazine | Apresoline | NAT2 | Cardiology | C | Yes |
| Isosorbide dinitrate–hydralazine | BiDil | NAT2 | Cardiology | C | No |
| Ranolazine | Ranexa | CYP3A4 | Cardiology | C | No |
| Ivabradine | Corlanor | CYP3A4 | Cardiology | C | No |
| Codeine | Tylenol #3 | CYP2D6 | Pain management | A | Yes |
| Tramadol | Ultram | CYP2D6 | Pain management | A | Yes |
| Hydrocodone | Norco | CYP2D6 | Pain management | C | No |
| Oxycodone | OxyContin | CYP2D6 | Pain management | C | No |
| Morphine | MS Contin | OPRM1 · COMT | Pain management | C | No |
| Methadone | Dolophine | CYP2B6 | Pain management | C | No |
| Fentanyl | Duragesic | CYP3A4 | Pain management | C | No |
| Buprenorphine | Suboxone | CYP3A4 | Pain management | C | No |
| Naltrexone | Revia | OPRM1 | Pain management | C | No |
| Celecoxib | Celebrex | CYP2C9 | Pain management | A | Yes |
| Ibuprofen | Advil | CYP2C9 | Pain management | A | No |
| Naproxen | Naprosyn | CYP2C9 | Pain management | C | No |
| Meloxicam | Mobic | CYP2C9 | Pain management | A | No |
| Piroxicam | Feldene | CYP2C9 | Pain management | A | No |
| Flurbiprofen | Ansaid | CYP2C9 | Pain management | A | No |
| Tenoxicam | Mobiflex | CYP2C9 | Pain management | A | No |
| Lornoxicam | Xefo | CYP2C9 | Pain management | A | No |
| Diclofenac | Voltaren | CYP2C9 | Pain management | A | No |
| Indomethacin | Indocin | CYP2C9 | Pain management | C | No |
| Aspirin | Bayer | PEAR1 | Pain management | C | No |
| Succinylcholine | Anectine | RYR1 · CACNA1S · BCHE | Anaesthesia | A | Yes |
| Mivacurium | Mivacron | BCHE | Anaesthesia | B | No |
| Sevoflurane | Ultane | RYR1 · CACNA1S | Anaesthesia | A | No |
| Desflurane | Suprane | RYR1 · CACNA1S | Anaesthesia | A | No |
| Isoflurane | Forane | RYR1 · CACNA1S | Anaesthesia | A | No |
| Halothane | Fluothane | RYR1 · CACNA1S | Anaesthesia | A | No |
| Propofol | Diprivan | CYP2B6 | Anaesthesia | C | No |
| Ketamine | Ketalar | CYP2B6 | Anaesthesia | C | No |
| Ropivacaine | Naropin | CYP1A2 | Anaesthesia | C | No |
| Nitrous oxide | — | MTHFR | Anaesthesia | C | No |
| Fluorouracil | Adrucil | DPYD | Oncology | A | Yes |
| Capecitabine | Xeloda | DPYD | Oncology | A | Yes |
| Tegafur | Teysuno | DPYD | Oncology | A | No |
| Irinotecan | Camptosar | UGT1A1 | Oncology | B | Yes |
| Sacituzumab govitecan | Trodelvy | UGT1A1 | Oncology | C | Yes |
| Belinostat | Beleodaq | UGT1A1 | Oncology | C | Yes |
| Nilotinib | Tasigna | UGT1A1 | Oncology | C | Yes |
| Pazopanib | Votrient | UGT1A1 · HLA-B*57:01 | Oncology | C | Yes |
| Tamoxifen | Nolvadex | CYP2D6 | Oncology | A | Yes |
| Letrozole | Femara | CYP2A6 | Oncology | C | No |
| Mercaptopurine | Purinethol | TPMT · NUDT15 | Oncology | A | Yes |
| Thioguanine | Tabloid | TPMT · NUDT15 | Oncology | A | Yes |
| Cisplatin | Platinol | TPMT | Oncology | C | No |
| Cyclophosphamide | Cytoxan | CYP2B6 | Oncology | C | No |
| Paclitaxel | Taxol | CYP2C8 | Oncology | C | No |
| Docetaxel | Taxotere | CYP3A4 | Oncology | C | No |
| Vincristine | Oncovin | CEP72 | Oncology | B | No |
| Doxorubicin | Adriamycin | RARG · SLC28A3 | Oncology | C | No |
| Daunorubicin | Cerubidine | RARG | Oncology | C | No |
| Methotrexate (high dose) | Trexall | SLCO1B1 · MTHFR | Oncology | B | No |
| Rasburicase | Elitek | G6PD | Oncology | A | Yes |
| Busulfan | Myleran | GSTA1 | Oncology | C | No |
| Etoposide | Vepesid | UGT1A1 | Oncology | C | No |
| Imatinib | Gleevec | ABCB1 | Oncology | C | No |
| Eltrombopag | Promacta | UGT1A1 | Haematology | C | Yes |
| Deferasirox | Exjade | UGT1A1 | Haematology | C | No |
| Hydroxyurea | Hydrea | HBG1 | Haematology | C | No |
| Tacrolimus | Prograf | CYP3A5 | Immunology | A | No |
| Cyclosporine | Neoral | CYP3A5 · ABCB1 | Immunology | C | No |
| Sirolimus | Rapamune | CYP3A5 | Immunology | C | No |
| Everolimus | Afinitor | CYP3A5 | Immunology | C | No |
| Mycophenolate | CellCept | UGT1A9 | Immunology | C | No |
| Azathioprine | Imuran | TPMT · NUDT15 | Immunology | A | Yes |
| Allopurinol | Zyloprim | HLA-B*58:01 | Rheumatology | A | Yes |
| Pegloticase | Krystexxa | G6PD | Rheumatology | B | Yes |
| Colchicine | Colcrys | CYP3A4 · ABCB1 | Rheumatology | C | No |
| Methotrexate | Rheumatrex | MTHFR | Rheumatology | B | No |
| Sulfasalazine | Azulfidine | NAT2 | Rheumatology | C | No |
| Hydroxychloroquine | Plaquenil | G6PD | Rheumatology | C | No |
| Leflunomide | Arava | CYP1A2 · DHODH | Rheumatology | C | No |
| Tofacitinib | Xeljanz | CYP2C19 | Rheumatology | C | No |
| Dapsone | Aczone | G6PD | Dermatology | B | Yes |
| Terbinafine | Lamisil | CYP2D6 | Dermatology | C | No |
| Isotretinoin | Accutane | CYP2C9 | Dermatology | C | No |
| Abacavir | Ziagen | HLA-B*57:01 | Infectious disease | A | Yes |
| Nevirapine | Viramune | CYP2B6 · HLA-B*35:01 | Infectious disease | B | No |
| Efavirenz | Sustiva | CYP2B6 | Infectious disease | A | No |
| Etravirine | Intelence | CYP2C19 | Infectious disease | C | No |
| Atazanavir | Reyataz | UGT1A1 | Infectious disease | A | No |
| Dolutegravir | Tivicay | UGT1A1 | Infectious disease | C | No |
| Raltegravir | Isentress | UGT1A1 | Infectious disease | C | No |
| Maraviroc | Selzentry | CCR5 | Infectious disease | B | Yes |
| Lopinavir–ritonavir | Kaletra | SLCO1B1 | Infectious disease | C | No |
| Tenofovir | Viread | ABCC2 | Infectious disease | C | No |
| Zidovudine | Retrovir | ABCC4 | Infectious disease | C | No |
| Ribavirin | Rebetol | ITPA | Infectious disease | B | No |
| Peginterferon alfa | Pegasys | IFNL3 | Infectious disease | B | No |
| Voriconazole | Vfend | CYP2C19 | Infectious disease | A | Yes |
| Itraconazole | Sporanox | CYP3A4 | Infectious disease | C | No |
| Isavuconazole | Cresemba | CYP3A4 | Infectious disease | C | No |
| Isoniazid | Nydrazid | NAT2 | Infectious disease | B | No |
| Rifampin | Rifadin | SLCO1B1 | Infectious disease | C | No |
| Primaquine | — | G6PD | Infectious disease | A | Yes |
| Tafenoquine | Arakoda | G6PD | Infectious disease | A | Yes |
| Chloroquine | Aralen | G6PD | Infectious disease | B | No |
| Quinine | Qualaquin | G6PD | Infectious disease | C | No |
| Sulfamethoxazole–trimethoprim | Bactrim | G6PD | Infectious disease | B | No |
| Sulfadiazine | — | G6PD | Infectious disease | C | No |
| Nitrofurantoin | Macrobid | G6PD | Infectious disease | C | Yes |
| Pyrimethamine | Daraprim | G6PD | Infectious disease | C | No |
| Ciprofloxacin | Cipro | CYP1A2 | Infectious disease | C | No |
| Artemether–lumefantrine | Coartem | CYP2D6 | Infectious disease | C | No |
| Flucloxacillin | Floxapen | HLA-B*57:01 | Infectious disease | C | No |
| Amoxicillin–clavulanate | Augmentin | HLA-DRB1 | Infectious disease | C | No |
| Gentamicin | Garamycin | MT-RNR1 | Infectious disease | A | No |
| Amikacin | Amikin | MT-RNR1 | Infectious disease | A | No |
| Tobramycin | Nebcin | MT-RNR1 | Infectious disease | A | No |
| Omeprazole | Prilosec | CYP2C19 | Gastroenterology | A | Yes |
| Esomeprazole | Nexium | CYP2C19 | Gastroenterology | A | Yes |
| Pantoprazole | Protonix | CYP2C19 | Gastroenterology | A | Yes |
| Lansoprazole | Prevacid | CYP2C19 | Gastroenterology | A | Yes |
| Dexlansoprazole | Dexilant | CYP2C19 | Gastroenterology | A | Yes |
| Rabeprazole | Aciphex | CYP2C19 | Gastroenterology | A | Yes |
| Ondansetron | Zofran | CYP2D6 | Gastroenterology | A | No |
| Tropisetron | Navoban | CYP2D6 | Gastroenterology | A | No |
| Dolasetron | Anzemet | CYP2D6 | Gastroenterology | C | Yes |
| Palonosetron | Aloxi | CYP2D6 | Gastroenterology | C | No |
| Metoclopramide | Reglan | CYP2D6 | Gastroenterology | C | Yes |
| Loperamide | Imodium | CYP2D6 | Gastroenterology | C | No |
| Eluxadoline | Viberzi | SLCO1B1 | Gastroenterology | C | Yes |
| Alosetron | Lotronex | CYP1A2 | Gastroenterology | C | No |
| Tolterodine | Detrol | CYP2D6 | Urology | C | Yes |
| Fesoterodine | Toviaz | CYP2D6 | Urology | C | Yes |
| Darifenacin | Enablex | CYP2D6 | Urology | C | No |
| Tamsulosin | Flomax | CYP2D6 | Urology | C | Yes |
| Sildenafil | Viagra | CYP3A4 | Urology | C | No |
| Theophylline | Theo-24 | CYP1A2 | Respiratory | C | No |
| Montelukast | Singulair | CYP2C8 | Respiratory | C | No |
| Zafirlukast | Accolate | CYP2C9 | Respiratory | C | No |
| Roflumilast | Daliresp | CYP2C19 | Respiratory | C | Yes |
| Salmeterol | Serevent | ADRB2 | Respiratory | C | No |
| Albuterol | Ventolin | ADRB2 | Respiratory | C | No |
| Ivacaftor | Kalydeco | CFTR | Respiratory | A | Yes |
| Lumacaftor–ivacaftor | Orkambi | CFTR | Respiratory | A | Yes |
| Elexacaftor–tezacaftor–ivacaftor | Trikafta | CFTR | Respiratory | A | Yes |
| Metformin | Glucophage | SLC22A1 | Endocrinology | C | No |
| Glipizide | Glucotrol | CYP2C9 | Endocrinology | C | No |
| Glimepiride | Amaryl | CYP2C9 | Endocrinology | C | No |
| Glyburide | Diabeta | CYP2C9 | Endocrinology | C | No |
| Gliclazide | Diamicron | CYP2C9 | Endocrinology | C | No |
| Tolbutamide | Orinase | CYP2C9 | Endocrinology | C | No |
| Repaglinide | Prandin | CYP2C8 · SLCO1B1 | Endocrinology | C | No |
| Pioglitazone | Actos | CYP2C8 | Endocrinology | C | No |
| Rosiglitazone | Avandia | CYP2C8 | Endocrinology | C | No |
| Methimazole | Tapazole | HLA-B*38:02 | Endocrinology | C | No |
| Eliglustat | Cerdelga | CYP2D6 | Metabolic | A | Yes |
| Sapropterin | Kuvan | PAH | Metabolic | B | Yes |
| Migalastat | Galafold | GLA | Metabolic | B | Yes |
| No medications match those filters. Try clearing one. | |||||
Showing all 263 entries
Reading the columns
CPIC level — A and B carry prescribing guidance strong enough to act on; C and D are informative but rarely change therapy on their own.
PGx on FDA label — whether the drug’s approved labelling includes pharmacogenomic information, from a dosing table to a boxed warning.
Find out which of these apply to you
